Seyfried Lab People


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People in the Seyfried Lab

Nick Seyfried
Assistant Professor
Director, ENNCF Proteomics Core
Nicholas T. Seyfried obtained his BS in biological chemistry from Boston College and his DPhil in Biochemistry from the University of Oxford. During his postdoctoral fellowship at Emory University School of Medicine he employed cell-based quantitative proteomics methodologies to characterize protein aggregation and post-translational modification events that underlie neurodegenerative diseases. He also developed immobilized metal affinity chromatography (IMAC) techniques for the enrichment of phosphopeptides from human brain tissue. Prior to this work, Dr. Seyfried held a postdoctoral research position in the Complex Carbohydrate Research Center at the University of Georgia. Here his research focused on the use of hydrogen/deuterium amide exchange Fourier transform mass spectrometry as a method to study protein-carbohydrate interactions. Dr. Seyfried is currently an assistant professor of Biochemistry and Neurology and is a member of the Center for Neurodegenerative Diseases.


Eric Dammer
Research Associate
Eric received a B.A. in liberal arts from Florida Gulf Coast University in 2003 and a Ph.D in Applied Biology from Georgia Tech in 2008 before joining Nicholas Seyfried as a fellow postdoc in the lab of Junmin Peng, where the focus of inquiry was ubiquitin-mediated proteostasis and on biomarkers of neurodegeneration in diseases such as ALS and Alzheimer Disease. As a postdoc, Eric has been awarded NINDS T32 and NIA F32 funding, respectively 1) to explore translational medicine with regards to hypothesized splicing defects in Alzheimer Disease, and 2) to study the mechanisms and effect of ubiquitin on aggregate prone protein clearance in ALS and associated dementia. As a graduate student, Eric studied the molecular genetics of steroid production in the adrenal cortex as regulated by peptide hormones, cAMP as a second messenger, and nuclear receptors found to utilize novel lipid ligands.


Duc Duong
Associate Director, ENNCF Proteomics Core
Duc graduated from Emory University in 2003 with a B.S. degree in computer science and has over 10 years of experience with cutting edge LC-MS/MS technologies. He has developed algorithms for extensive data processing and peptide/protein quantification. Duc works in collaboration on a variety of research projects with research investigators at the Center for Neurodegenerative Disease and throughout the Emory University community.


Isaac Bishof
Graduate Student
Isaac graduated from Florida State University in 2011 with a degree in biochemistry and is now working towards his PhD at Emory University. Isaac's research focuses on RNA binding proteins and mechanisms of protein aggregation in neurodegenerative diseases.


Ian Diner
Lab Manager
Ian graduated from Emory University in 2012 with a double major in Neuroscience and Behavioral Biology (NBB) and Chemistry. His research focuses on the study of protein aggregation events in neurodegenerative diseases, with particular emphasis on RNA binding proteins. Ian plans to enroll in a PhD program beginning in 2015.

Previous Members

Andrew Lee
Research Specialist
Andrew is currently a graduate student at Duke University.

Rosie Tang
Undergraduate Researcher
Rosie has graduated from Emory with a B.S in Neuroscience and Behavioral Biology and is attending medical school.

John Le
Computer Engineer
John is attending Georgia State University for a degree in Computer Information Systems.

Chelsea Dunn
Research Intern
Chelsea is completing her undergraduate degree at Hampshire College in May 2014 with a focus in biochemistry, neuroscience, and improvisational cello performance. She is interested in furthering a career in biochemistry research.

Information for Applicants

Prospective graduate students should apply to the Graduate Division of Biological and Biomedical Sciences (GDBBS). Dr. Seyfried is a training faculty member of the Biochemistry, Cell and Developmental Biology (BCDB) and Neuroscience programs within the GDBBS.

Interested postdoctoral fellows should contact Dr. Seyfried directly by email. Applications should include a summary of research experience and interests, and a C.V. with contact details for at least three potential references. Candidates with their own funding or interested in applying for fellowships should contact Dr. Seyfried at any time.

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